Offering of Isaac
"And they came to the place which God had told him of. And Abraham built the altar there, and laid the wood in order, and bound Isaac his son, and laid him on the altar, upon the wood. And Abraham stretched forth his hand, and took the knife to slay his son. And the angel of Jehovah called unto him out of heaven, and said, Abraham, Abraham. And he said, Here I am. And he said, Lay not thy hand upon the lad, neither do thou anything unto him. For now I know that thou fearest God, seeing thou hast not withheld thy son, thine only son, from me." Genesis 22:9-12
This sculpture is a Bronze-relief by Brunellesco. There is a similar sculpture done by Ghiberti. It can now be found in the National Museum in Florence, Italy.