Acetic acid (dilute) causes the nucleus of the red blood cells in the frog to become more clearly defined; if the action is prolonged, the nucleus becomes strongly granulated, and all the coloring matter seems to be concentrated in it, the surrounding cell substance and outline of the cell becoming almost invisible; after a time the cells lose their color altogether. The cells shown represent the successive stages of change. A similar loss of color occurs in the red cells of human blood, which , however, from the absence of nuclei, seem to disappear entirely.

Effect of Acetic Acid on Red Blood Cells

Acetic acid (dilute) causes the nucleus of the red blood cells in the frog to become more clearly defined;…

A 2 percent solution of boric acid applied to nucleated red blood cells of a frog will cause the concentration of all he coloring matter in the nucleus; the colored body thus formed gradually quits its central position , and comes to be partly, sometime entirely, protruded from the surface of the now colorless cell. When applied to non-nucleated mammalian corpuscle its effect merely resembles that of other dilute acids.

Effect of Boric Acid on Red Blood Cells

A 2 percent solution of boric acid applied to nucleated red blood cells of a frog will cause the concentration…

If the red blood cells of a frog be first exposed to the action of water vapor (which renders their outer pellicle more readily permeable to gases), and then acted on by carbonic acid, the nuclei immediately become clearly defined and strong granulated, when air or oxygen is admitted the original appearance is at once restored. The upper and lower cells in this figure show the effect of carbonic acid; the middle one the effect of the readmission of air. The effects can be reproduced five or six times in succession. If, however, the action of the carbonic acid be much prolonged, the granulated of the nucleus become permanent; it appears to depend on a coagulation of the paraglobulin.

Effect of Gases on Red Blood Cells

If the red blood cells of a frog be first exposed to the action of water vapor (which renders their…

When a 2 percent fresh solution of tannic acid is applied to frog's blood it causes the appearance of a sharply defined little knob, projecting from the free surface (Robert's macula): the coloring matter becomes at the same concentrated in the nucleus, which grows more distinct. A somewhat similar effect is produced on the human blood corpuscle.

Effect of Tannin on Red Blood Cells

When a 2 percent fresh solution of tannic acid is applied to frog's blood it causes the appearance of…